Phyllanthus (Euphorbiaceae) is widely distributed in tropical and subtropical areas, including Vietnam, where it is considered a valuable medicinal herb. Numerous bioactive compounds from Phyllanthus species have been identified, demonstrating pharmacological effects such as antiallergic, anti-inflammatory, antioxidant, antidiabetic, anticancer, antiviral, antibacterial, antimalarial, and wound healing activities. This review provides a comprehensive summary of Phyllanthus genus and its pharmaceutical properties, emphasizing the methodologies used for bioactive compound extraction and evaluation, as well as their clinical relevance.

Diabetes affected about 537 million adults aged 20 to 79 in 2021. Higher vegetable intake helps to manage type 2 diabetes mellitus. Thus, this research aimed to recognize and record the vegetable species currently sold in Sri Lanka's Vavuniya District. At least three fieldwork visits were made between January 2019 and January 2022 to each of the Vavuniya District's major market sites, as well as the neighboring vegetable shops and street stalls. Until June 2022, published relevant research papers were searched in the Web of Science, PubMed, and ScienceDirect databases for the recorded vegetable species in this study to assess the antidiabetic scientific proof. This study recognized and recorded 72 vegetable species from 25 families. Consequently, a study of the literature on 65 vegetable species found that most of the vegetable species had in vivo (37%), followed by clinical (15%), and in vitro (14%) scientific evidence, and six antidiabetic active substances were isolated from the analyzed vegetable species. This work establishes the foundation for additional studies on the fruit species traded in Vavuniya District.

Indigofera aspalathoides Vahl ex DC. belongs to the Fabaceae family. I. aspalathoides is applied to heal tumors, inflammations, diabetes, leprosy, and kidney illnesses in traditional medicines. Compounds including kaempferol, kaempferol 5-O-β-D-glucopyranoside, 5,4'-dihydroxy 6,8-dimethoxy 7-O-rhamnosyl flavone, indigocarpan, and mucronulatol have isolated from this plant species. Hitherto, there is no comprehensive review available regarding the reported bioactivities of I. aspalathoides. Thus, this article goals to analyze, summarize and document the published bioactivities-related publications. Electronic databases the Web of Science, Scopus, ScienceDirect, and PubMed used to find relevant publications from 1900 to December 2020. Thus far, only in vivo and in vitro scientific evidence levels of bioactivities are available. I. aspalathoides holds such as anti-inflammatory, anticancer, antihepatotoxic, anti-arthritic, immunomodulatory, and antidiabetic properties. Overall, immunomodulatory, anti-inflammatory, and anticancer compounds have been isolated from this plant species Therefore, additional bioactivity and phytochemical-related researches would need to perform to generate more scientific evidence for other applications. This work will be useful for further bioactivity and phytochemical studies using this plant species.